BDBM50005459 4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid::CHEMBL9485::CR 1409

SMILES CCCCCN(CCCCC)C(=O)[C@@H](CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IEKOTSCYBBDIJC-UHFFFAOYSA-N

Data  4 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50005459   

TargetCholecystokinin receptor type A(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 66nMAssay Description:Inhibition of [125I]Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 1.24E+4nMAssay Description:Compound was evaluated for the binding affinity against CCK A receptor in cortical cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [3H](N-methyl-N-leucine)-CCK-8 to Cholecystokinin type B receptor of guinea pig brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I](BH)-CCK-8 to Cholecystokinin type A receptor in rat pancreatic aciniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCholecystokinin receptor type A(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataIC50: 66nMAssay Description:Compound was evaluated for the binding affinity against CCK A receptor in pancreatic acinar cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H]L-364718 binding to cholecystokinin type A receptor in rat pancreas membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(CHEMBL9485 | CR 1409 | 4-(3,4-Dichloro-benzoylamin...)
Affinity DataKi:  2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed