BDBM50072775 2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol::5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxy-propyl)-cyclohexyl]-phenol::5-(1,1-Dimethyl-heptyl)-2-[(4R,6R)-5-hydroxy-2-((R)-3-hydroxy-propyl)-cyclohexyl]-phenol::CHEMBL48552::CP-55940::CP-55940 [(-)-AC],XIV::CP55,940::CP55940::ChEMBL_75020
SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
InChI Key InChIKey=YNZFFALZMRAPHQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 190 hits for monomerid = 50072775
Affinity DataEC50: 19.9nMAssay Description:Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 1.80nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 1.20nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 3.30nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 0.900nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataKd: 2.90nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
Affinity DataEC50: 0.350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Gbeta1gamma2 and RSG4 assessed as degradation of [gamma-33P]GTP after 20 m...More data for this Ligand-Target Pair
Affinity DataEC50: 12.9nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Gbeta1gamma2 and RSG4 assessed as degradation of [gamma-33P]GTP after 20 m...More data for this Ligand-Target Pair
Affinity DataEC50: 9.30nMAssay Description:Partial agonist activity at human cannabinoid CB2 receptor expressed in CHO-K1 cells assessed as [S35]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Partial agonist activity at human cannabinoid CB1 receptor expressed in CHO-K1 cells assessed as [S35]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...More data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...More data for this Ligand-Target Pair
Affinity DataEC50: 0.576nMAssay Description:Agonist activity at human CB2 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.437nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]CP 55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inverse agonist activity at human cannabinoid CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation af...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]BMS-725519 from rat brain CB1 receptor after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Agonist activity at MF1 mouse brain CB1 receptor assessed as induction of [35S]GTPgammaS binding after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.28nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.280nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human recombinant CB1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as increase in forskolin-induced cAMP production after 45 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 5.99E+3nMAssay Description:Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes assessed as increase in forskolin-stimulated cAMP production after 45 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10.3nMAssay Description:Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.66nMAssay Description:Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.28nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair