BDBM50284689 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl)-phenoxymethyl]-phenyl}-vinyl)-quinoline::CHEMBL28902::CP-96486

SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)cc1

InChI Key InChIKey=ZKHUZIGQNHJVGZ-UHFFFAOYSA-N

Data  2 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50284689   

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article