BDBM50049207 2-Butyl-6-(1-methoxy-1-methyl-ethyl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one::CHEMBL275875::CL-329167

SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)OC

InChI Key InChIKey=XZCUIMYYMKTCBA-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049207   

TargetType-1 angiotensin II receptor(Rabbit)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50049207(2-Butyl-6-(1-methoxy-1-methyl-ethyl)-3-[2'-(1H-tet...)
Affinity DataKd:  9.77nMAssay Description:Antagonist activity at angiotensin AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50049207(2-Butyl-6-(1-methoxy-1-methyl-ethyl)-3-[2'-(1H-tet...)
Affinity DataIC50: 31nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50049207(2-Butyl-6-(1-methoxy-1-methyl-ethyl)-3-[2'-(1H-tet...)
Affinity DataIC50: 6nMAssay Description:Binding affinity to angiotensin AT1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50049207(2-Butyl-6-(1-methoxy-1-methyl-ethyl)-3-[2'-(1H-tet...)
Affinity DataIC50: 6nMAssay Description:In vitro Angiotensin II receptor antagonist activity in rat adrenal cortex tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article