BDBM50287397 CGP-49823::CHEMBL290364::{(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-piperidin-1-yl}-(3,5-dimethyl-phenyl)-methanone::{(R)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-piperidin-1-yl}-(3,5-dimethyl-phenyl)-methanone

SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12

InChI Key InChIKey=WQZUOBIIPDZRJP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50287397   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against NK1 receptor by displacement of [3H]SP from bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 13nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 2.65E+3nMAssay Description:Compound was tested for inhibition of [125I]eledoisin radioligand binding to NK3 receptor from gerbil cortexMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSubstance-K receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 2.79E+3nMAssay Description:Compound was tested for inhibition of [125I]NKA radioligand binding to NK2 receptor from bovine bladderMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 12nMAssay Description:Tested for the inhibitory potency against Neurokinin 1 NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 12nMAssay Description:Tested for the binding affinity against neurokinin NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 55nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In DepthDetails Article