BDBM82018 CAS_790::CHEMBL1427::Hypoxanthine::NSC_790

SMILES O=c1[nH]cnc2nc[nH]c12

InChI Key InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N

Data  2 KI  1 Kd  2 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82018   

TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
Affinity DataKd:  680nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
Affinity DataKi:  1.70E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 82018   

CellPurine nucleoside phosphorylase(Human)
Albert Einstein College of Medicine

SyringePNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
ITC DataΔG°: -7.40kcal/mole logk: 2.70E+5
pH: 7.4 T: 25.00°C 
In DepthDetails Article
PubMed
CellPurine nucleoside phosphorylase(Human)
Albert Einstein College of Medicine

SyringePNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
ITC DataΔH°: -30.6kcal/mole
pH: 7.4 T: 27.00°C 
In DepthDetails Article
PubMed