BDBM50565694 Balsalazide::CHEBI:267413

SMILES OC(=O)CCNC(=O)c1ccc(cc1)\N=N\c1ccc(O)c(c1)C(O)=O

InChI Key InChIKey=IPOKCKJONYRRHP-UHFFFAOYSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50565694   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human SIRT5 using flour de lys succinyl as substrate in presence of NAD+ by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of SIRT5 (unknown origin) assessed as reduction in GGQSLKFGKG formation using GGQSLK[succ]FGKG as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of SIRT5 (unknown origin) desuccinylation activityMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human Sirt5 incubated for 1 hr by FLUOR DE LYS fluorometric microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataEC50:  8.80E+3nMAssay Description:Binding affinity to Sirt5 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNucleoside diphosphate kinase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataEC50:  4.58E+4nMAssay Description:Binding affinity to NME4 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutaryl-CoA dehydrogenase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataEC50:  1.73E+4nMAssay Description:Binding affinity to GCDH in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50565694(CHEBI:267413 | Balsalazide)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human SIRT5More data for this Ligand-Target Pair
In DepthDetails
PubMed