BDBM178098 BRD4097::US11377423, Compound 9

SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(C)cc1N

InChI Key InChIKey=HRMBUIZWNJTBSE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 178098   

TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.33E+4nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.33E+4nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.33E+4nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.30E+4nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

LigandPNGBDBM178098(BRD4097 | US11377423, Compound 9)
Affinity DataIC50: 3.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent