BDBM50220841 BMS-262084::CHEMBL71037

SMILES [#6]C([#6])([#6])[#7]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#7]-1-[#6@@H](-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6]-1=O)-[#6](-[#8])=O

InChI Key InChIKey=PHOILWYOWQIAMD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50220841   

TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 50nMAssay Description:Inhibition of trypsin (unknown origin) using Chromozyme-TRY substrate incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase delta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 5nMAssay Description:Inhibition of human lung tryptase using Z-glypro-arg-AMC incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human factor 11a using S-2366 substrate incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human FXIaMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTryptase delta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 5nMAssay Description:Inhibition of human tryptaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 50nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails
PubMed