BDBM50120368 (2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carbonyl)-3-(3-guanidino-propyl)-4-oxo-azetidine-2-carboxylic acid::(3S,4R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carbonyl)-3-(3-guanidino-propyl)-4-oxo-azetidine-2-carboxylic acid::(R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carbonyl)-3-(3-guanidino-propyl)-4-oxo-azetidine-2-carboxylic acid::1-(4-tert-Butylcarbamoyl-piperazine-1-carbonyl)-3-(3-guanidino-propyl)-4-oxo-azetidine-2-carboxylic acid::BMS-262084::CHEMBL71037

SMILES CC(C)(C)NC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CCCNC(N)=N)C1=O)C(O)=O

InChI Key InChIKey=MFTQITSPGQORDA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50120368   

TargetSerine protease 1(Bovine)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 8.25E+3nMAssay Description:Inhibitory activity against tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 135nMAssay Description:Inhibitory activity against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 2.80nMAssay Description:Irreversible inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed