BDBM50526695 BI-78D3::CHEMBL508280

SMILES Oc1nnc(Sc2ncc(s2)[N+]([O-])=O)n1-c1ccc2OCCOc2c1

InChI Key InChIKey=QFRLDZGQEZCCJZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50526695   

TargetMitogen-activated protein kinase 8(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50526695(CHEMBL508280 | BI-78D3)
Affinity DataIC50: 280nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50526695(CHEMBL508280 | BI-78D3)
Affinity DataIC50: 32nMAssay Description:Inhibition of JNK3 (unknown origin) irradiated with 400 nm lightMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50526695(CHEMBL508280 | BI-78D3)
Affinity DataIC50: 507nMAssay Description:Inhibition of JNK3 (unknown origin) in darkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Rat)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50526695(CHEMBL508280 | BI-78D3)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to rat full-length ERK2 using FQRKTLQRRNLKGLNLNL-XXX-TGPLSPGPF peptide as substrate in presence of [gamma33P]ATP by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed