BDBM99467 US8497274, 3

SMILES CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3C#N)c2)c1Cl

InChI Key InChIKey=GXLAKHKBZJXGHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99467   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99467(US8497274, 3)
Affinity DataIC50: 300nMAssay Description:MEK phosphorylation inhibition activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
Go to US Patent