BDBM993 4,7-dihydroxy-3-[4-(2-methoxyphenyl)butyl]-2H-chromen-2-one::Hydroxycoumarin deriv. 31

SMILES COc1ccccc1CCCCc1c(O)c2ccc(O)cc2oc1=O

InChI Key InChIKey=DPYHGUIDBOZDPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 993   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM993(4,7-dihydroxy-3-[4-(2-methoxyphenyl)butyl]-2H-chro...)
Affinity DataIC50: 520nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM993(4,7-dihydroxy-3-[4-(2-methoxyphenyl)butyl]-2H-chro...)
Affinity DataIC50: 520nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed