BDBM99145 US8497265, 894

SMILES CC(=O)N1CCC(CC1)c1nccnc1OC1CN(C1)c1ccc2ccccc2n1

InChI Key InChIKey=QHXMZSJCPZCMCR-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 99145   

LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 8.39nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE9A2 using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 29nMAssay Description:Inhibition of human PDE10A2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE11A4 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE1B using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE2A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE3A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE4D2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE5A using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE8A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM99145(US8497265, 894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE7A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed