BDBM98898 US8497265, 224
SMILES OCC1CCN(CC1)c1nc2ccccc2nc1OC1CN(C1)c1ccc2ccccc2n1
InChI Key InChIKey=YGQUPXYJXOSCNR-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 98898
Affinity DataIC50: 9.75nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PDE10A2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human PDE11A4 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.61E+3nMAssay Description:Inhibition of human PDE1B using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human PDE2A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE3A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of human PDE4D2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE5A using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE7A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE8A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE9A2 using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair