BDBM98891 US8497265, 217::US8497265, 239

SMILES c1ccc2c(c1)ccc(n2)N3CC(C3)Oc4c(nccn4)N5CCC(CC5)CO

InChI Key InChIKey=VIXNRMUNIQTMQR-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 98891   

LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 2.30nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 23.3nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PDE10A2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE11A4 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of human PDE1B using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human PDE2A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE3A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human PDE4D2 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE5A using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE7A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE8A1 using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
LigandPNGBDBM98891(US8497265, 239 | US8497265, 217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDE9A2 using FAM-cGMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed