BDBM98602 3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonylamino)propanoyl]amino]acetyl]amino]phenyl]-4-methoxy-benzamide::US8476306, 11

SMILES NC(CNS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=GQVFTAXOXBLSOQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98602   

TargetUrokinase plasminogen activator surface receptor(Rat)
The Medicines

US Patent
LigandPNGBDBM98602(3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...)
Affinity DataKi:  180nM ΔG°:  -9.16kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetSerine protease 1(Rat)
The Medicines

US Patent
LigandPNGBDBM98602(3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...)
Affinity DataKi:  180nM ΔG°:  -9.16kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetPlasminogen(Rat)
The Medicines

US Patent
LigandPNGBDBM98602(3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...)
Affinity DataKi:  9.60E+3nM ΔG°:  -6.82kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetProthrombin(Rat)
The Medicines

US Patent
LigandPNGBDBM98602(3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.79kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent