BDBM98582 2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]sulfamoylmethyl]benzoic acid::US8476306, 6.7

SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2C(O)=O)cc1

InChI Key InChIKey=IYWSRHAQECQVEQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98582   

TargetUrokinase plasminogen activator surface receptor(Rat)
The Medicines

US Patent
LigandPNGBDBM98582(2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  370nM ΔG°:  -8.74kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetSerine protease 1(Rat)
The Medicines

US Patent
LigandPNGBDBM98582(2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  2.40E+3nM ΔG°:  -7.64kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetProthrombin(Rat)
The Medicines

US Patent
LigandPNGBDBM98582(2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  5.60E+4nM ΔG°:  -5.78kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
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TargetPlasminogen(Rat)
The Medicines

US Patent
LigandPNGBDBM98582(2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  2.20E+5nM ΔG°:  -4.97kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent