BDBM979 4-hydroxy-3-[4-(4-methoxyphenyl)butyl]-2H-chromen-2-one::Hydroxycoumarin deriv. 17

SMILES COc1ccc(CCCCc2c(O)c3ccccc3oc2=O)cc1

InChI Key InChIKey=YCGODPLRLBRRLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 979   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM979(4-hydroxy-3-[4-(4-methoxyphenyl)butyl]-2H-chromen-...)
Affinity DataIC50: 1.00E+5nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2004
Entry Details Article
PubMed