BDBM97464 US8470800, A::US8609833, 17::US8609833, 86

SMILES O[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12

InChI Key InChIKey=AQLVRTWKJDTWQQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 97464   

TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  0.970nM ΔG°:  -11.4kcal/molepH: 7.4 T: 2°CAssay Description:Membranes for radioligand binding experiments are prepared from fresh or frozen cells as described in Klotz et al., Naunyn-Schmiedeberg's Arch. Pharm...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  0.970nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  0.970nMAssay Description:Binding affinity to adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  0.970nMAssay Description:Binding affinity to A1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  704nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosine receptor A2(Human)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8609833, 17 | US8470800, A | US8609833, 86)
Affinity DataKi:  4.69E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails
US Patent