BDBM96413 6-(2-furanyl)-3-methyl-1-phenyl-4-pyrazolo[3,4-b]pyridinecarboxylic acid::6-(2-furyl)-3-methyl-1-phenyl-pyrazolo[3,4-b]pyridine-4-carboxylic acid::6-(furan-2-yl)-3-methyl-1-phenyl-pyrazolo[3,4-b]pyridine-4-carboxylic acid::6-(furan-2-yl)-3-methyl-1-phenylpyrazolo[3,4-b]pyridine-4-carboxylic acid::MLS000060726::SMR000066316::US9394303, 2::cid_2998778

SMILES Cc1nn(-c2ccccc2)c2nc(cc(C(O)=O)c12)-c1ccco1

InChI Key InChIKey=ZOUZSYLRQPADOJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 96413   

TargetHuntingtin(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96413(SMR000066316 | 6-(2-furanyl)-3-methyl-1-phenyl-4-p...)
Affinity DataIC50: 1.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mouse)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM96413(SMR000066316 | 6-(2-furanyl)-3-methyl-1-phenyl-4-p...)
Affinity DataKi:  4.25E+3nM ΔG°:  -7.32kcal/mole IC50: 2.21E+4nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent