BDBM9505 N-(Aryl)-thiazole-5-carboxamide 17::N-[4-(chlorodifluoromethoxy)phenyl]-4-[2-(pyridin-4-yl)ethyl]-1,3-thiazole-5-carboxamide

SMILES FC(F)(Cl)Oc1ccc(NC(=O)c2scnc2CCc2ccncc2)cc1

InChI Key InChIKey=WXIKJWRTWUAZJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9505   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9505(N-[4-(chlorodifluoromethoxy)phenyl]-4-[2-(pyridin-...)
Affinity DataIC50: 110nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9505(N-[4-(chlorodifluoromethoxy)phenyl]-4-[2-(pyridin-...)
Affinity DataIC50: 760nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed