BDBM9504 2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)benzamide::CHEMBL202011::anthranyl amide derivative D

SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1

InChI Key InChIKey=QPJBZGJXBJLNQV-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 9504   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 160nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 32nMT: 2°CAssay Description:In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against VEGFR-1 using 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against VEGFR-2 using 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR2 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 160nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 160nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9504(CHEMBL202011 | 2-[(pyridin-4-ylmethyl)amino]-N-(qu...)
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed