BDBM9498 N-(4-tert-butylphenyl)-4-[2-(quinolin-4-yl)ethyl]-1,3-thiazole-5-carboxamide::N-(Aryl)-thiazole-5-carboxamide 12

SMILES CC(C)(C)c1ccc(NC(=O)c2scnc2CCc2ccnc3ccccc23)cc1

InChI Key InChIKey=SMSPSBPTIAPATO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9498   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

LigandPNGBDBM9498(N-(4-tert-butylphenyl)-4-[2-(quinolin-4-yl)ethyl]-...)
Affinity DataIC50: 2.51E+3nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

LigandPNGBDBM9498(N-(4-tert-butylphenyl)-4-[2-(quinolin-4-yl)ethyl]-...)
Affinity DataIC50: 5.46E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed