BDBM9473 4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one::CHEMBL225178::Coumarin deriv. 22

SMILES O=c1cc(OCCn2ccnc2)c2ccccc2o1

InChI Key InChIKey=MXJNKMWQNZHBOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9473   

TargetAromatase(Human)
University of Bari

LigandPNGBDBM9473(CHEMBL225178 | 4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-c...)
Affinity DataIC50: 760nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bari

LigandPNGBDBM9473(CHEMBL225178 | 4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-c...)
Affinity DataAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
University of Bari

LigandPNGBDBM9473(CHEMBL225178 | 4-[2-(1H-Imidazol-1-yl)ethoxy]-2H-c...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed