BDBM92918 Benzofuranone, 7

SMILES COc1ccc2OC(=O)C3(CC(C)c4ccccc34)c2c1

InChI Key InChIKey=GOWNABBGKSIXRG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92918   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Max Planck Research

LigandPNGBDBM92918(Benzofuranone, 7)
Affinity DataKi:  2.10E+4nM ΔG°:  -5.95kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Human)
Max Planck Research

LigandPNGBDBM92918(Benzofuranone, 7)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed