BDBM92915 Aryl 1-indanylketone, 4

SMILES COc1ccc(cc1C(=O)C1CCc2ccccc12)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=AIZQSTZVLBDALQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92915   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  1.20E+3nM ΔG°:  -7.53kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to CypA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Human)
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  2.10E+3nM ΔG°:  -7.22kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Human)
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to CypB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed