BDBM92914 Aryl 1-indanylketone, 3

SMILES COc1ccc(F)cc1-c1cc(N)c(O)c(c1)C(=O)C1CCc2ccccc12

InChI Key InChIKey=AHJXIVLCWQDTNS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 92914   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Max Planck Research

LigandPNGBDBM92914(Aryl 1-indanylketone, 3)
Affinity DataKi:  1.70E+3nM ΔG°:  -7.34kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM92914(Aryl 1-indanylketone, 3)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human Pin1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Human)
Max Planck Research

LigandPNGBDBM92914(Aryl 1-indanylketone, 3)
Affinity DataKi:  8.60E+3nM ΔG°:  -6.44kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMed