BDBM92856 Nicotinamidase Inhibitor, 23::PncA Inhibitor, 5

SMILES N#Cc1cccnc1

InChI Key InChIKey=GZPHSAQLYPIAIN-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92856   

TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM92856(PncA Inhibitor, 5 | Nicotinamidase Inhibitor, 23)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinamidase(Baker's yeast)
Cornell University

LigandPNGBDBM92856(PncA Inhibitor, 5 | Nicotinamidase Inhibitor, 23)
Affinity DataKi:  8.50E+4nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyrazinamidase/nicotinamidase, PncA protein(Borrelia burgdorferi)
Cornell University

LigandPNGBDBM92856(PncA Inhibitor, 5 | Nicotinamidase Inhibitor, 23)
Affinity DataKi:  2.00E+6nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsochorismatase family protein(Streptococcus pneumoniae)
Cornell University

LigandPNGBDBM92856(PncA Inhibitor, 5 | Nicotinamidase Inhibitor, 23)
Affinity DataKi:  5.00E+5nMAssay Description:Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine

LigandPNGBDBM92856(PncA Inhibitor, 5 | Nicotinamidase Inhibitor, 23)
Affinity DataKi:  1.40E+5nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed