BDBM92603 DHOD Inhibitor, 2::US8703811, 3

SMILES CCCCCC1CCCc2c(O)c3ccccc3nc12

InChI Key InChIKey=BLBSNYYRLAWWDS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 92603   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 340nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 110nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 510nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 3.00E+4nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 340nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 110nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 510nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDihydroorotate dehydrogenase (fumarate)(Baker's yeast)
Genzyme

US Patent
LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM92603(US8703811, 3 | DHOD Inhibitor, 2)
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
US Patent