BDBM91670 N-aryl-4-aryl-1,3-thiazole-2-amine, 26

SMILES Nc1ccc(Nc2nc(cs2)-c2ccc(Br)cc2)cc1

InChI Key InChIKey=UFDARRZTRWZSHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 91670   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Korea Research Institute of Chemical Technology

LigandPNGBDBM91670(N-aryl-4-aryl-1,3-thiazole-2-amine, 26)
Affinity DataIC50: 201nMpH: 7.4 T: 2°CAssay Description:5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2012
Entry Details Article
PubMed