BDBM89825 2-(4-Fluoro-phenyl)-chromen-4-one::2-(4-fluorophenyl)-1-benzopyran-4-one::2-(4-fluorophenyl)chromen-4-one::2-(4-fluorophenyl)chromone::MLS000526645::SMR000117119::cid_261391

SMILES c1ccc2c(c1)C(=O)C=C(O2)c3ccc(cc3)F

InChI Key InChIKey=ZHXIMGYEMBZGOI-UHFFFAOYSA-N

Data  5 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 89825   

TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 1.92E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHeat shock protein hsp-16.2(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 6.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)