BDBM8945 7-Hydroxy-2-(1H-imidazol-5-ylmethyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::7-hydroxy-2-(1H-imidazol-5-ylmethyl)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-one::GW113 analog 14

SMILES COc1cc2CCC(Cc3cnc[nH]3)C(=O)c2cc1O

InChI Key InChIKey=WELZQXLNHFGFLE-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8945   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8945(7-hydroxy-2-(1H-imidazol-5-ylmethyl)-6-methoxy-1,2...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8945(7-hydroxy-2-(1H-imidazol-5-ylmethyl)-6-methoxy-1,2...)
Affinity DataIC50: 6.40E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed