BDBM8883 5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)methyl]-1H-imidazole::5-{[(1E)-5-bromo-2,3-dihydro-1H-inden-1-ylidene]methyl}-1H-imidazole::Imidazolylmethyleneindane 9a::Imidazolylmethyleneindane 9b

SMILES Brc1ccc2C(CCc2c1)=Cc1cnc[nH]1

InChI Key InChIKey=SNWLVVNOSVKKRA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8883   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 26.2nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 23.5nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 92.8nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 10.3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 27nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataIC50: 100nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed