BDBM8876 (1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carbonitrile::(1E)-1-(1H-imidazol-5-ylmethylidene)-2,3-dihydro-1H-indene-5-carbonitrile::Imidazolylmethyleneindane 5a::Imidazolylmethyleneindane 5b

SMILES N#Cc1ccc2C(CCc2c1)=Cc1cnc[nH]1

InChI Key InChIKey=FFOSLNTUQPRRRB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8876   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 12.3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 35.9nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 35.7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 119nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataIC50: 15nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8876(Imidazolylmethyleneindane 5b | (1E)-1-(1H-imidazol...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed