BDBM8871 5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemethyl]-1H-imidazole::5-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]-1H-imidazole::Imidazolylmethylenetetrahydronaphthalene 1a::Imidazolylmethylenetetrahydronaphthalene 1b

SMILES C1CC(=Cc2cnc[nH]2)c2ccccc2C1

InChI Key InChIKey=LBBCKDMLQODDIG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8871   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 31.4nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 24.8nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 9.60nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 226nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 190nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed