BDBM87168 CHEMBL1254576::N-[2-[1-(4-bromophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide;2,2,2-trifluoroacetic acid::N-[2-[1-(4-bromophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-3-quinolinecarboxamide;2,2,2-trifluoroacetic acid::N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide;2,2,2-trifluoroacetic acid::VU0402726-1::cid_53469971

SMILES Brc1ccc(cc1)N1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1

InChI Key InChIKey=RASKUFRIXVZDBS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 87168   

TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 360nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 130nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 3.04E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 2.70E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87168(N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4....)
Affinity DataIC50: 360nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed