BDBM87135 CHEMBL1254909::N-[2-[1-(3,4-difluorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid::N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-2-naphthalenecarboxamide;2,2,2-trifluoroacetic acid::N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide;2,2,2-trifluoroacetic acid::N-[2-[1-[3,4-bis(fluoranyl)phenyl]-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::VU0405247-1::cid_46939579

SMILES Fc1ccc(cc1F)N1CNC(=O)C11CCN(CCNC(=O)c2ccc3ccccc3c2)CC1

InChI Key InChIKey=SGQZPQLYBRRDMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 87135   

TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 115nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 98nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 2.00E+4nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 2.81E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87135(CHEMBL1254909 | VU0405247-1 | N-[2-[1-(3,4-difluor...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed