BDBM86773 Phthalonitrile analogue, 4b

SMILES N#Cc1ccc(OCc2ccccc2)cc1C#N

InChI Key InChIKey=PCNDQXNVUWDUQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86773   

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM86773(Phthalonitrile analogue, 4b)
Affinity DataIC50: 1.79E+3nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM86773(Phthalonitrile analogue, 4b)
Affinity DataIC50: 7.90nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM86773(Phthalonitrile analogue, 4b)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed