BDBM86697 4-TrifluoromethylBZT::8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane::CHEMBL332772

SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=KFYINOIVXGBXKZ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86697   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86697(8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-meth...)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86697(8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-meth...)
Affinity DataKi:  541nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86697(8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-meth...)
Affinity DataKi:  635nMAssay Description:Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86697(8-Methyl-3-[phenyl-(4-trifluoromethyl-phenyl)-meth...)
Affinity DataKi:  1.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2012
Entry Details Article
PubMed