BDBM86428 SB-258585

SMILES COc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1CCN(C)CC1

InChI Key InChIKey=BDHMSYNBSBZCAF-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 86428   

Target5-hydroxytryptamine receptor 6(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Mouse)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  0.75nMAssay Description:Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of serotonin-induced cAMP accumulation by HTRF as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  1.82nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  2.29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Mouse)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed