BDBM86345 Phosphodiester analog, 6::Phosphodiester analog, 6(S4A)

SMILES COCCOCCOCCOCCOCCOCCOCCOCCC(=O)N1CCCC1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CP(O)(O)=O)C(N)=O

InChI Key InChIKey=WLTDRCJNNFNMFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86345   

TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

LigandPNGBDBM86345(Phosphodiester analog, 6(S4A) | Phosphodiester ana...)
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:The evaluation of Plk1 PBD binding affinities of the synthetic compounds using an ELISA-based 96-well assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

LigandPNGBDBM86345(Phosphodiester analog, 6(S4A) | Phosphodiester ana...)
Affinity DataIC50: 9.00E+3nMpH: 8.0 T: 2°CAssay Description:The evaluation of Plk1 PBD binding affinities of the synthetic compounds using an ELISA-based 96-well assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed