BDBM85278 HEA derivative, 7e

SMILES Cc1ccc(cc1)S(=O)(=O)NCC(CN1CCOCC1)OP(O)(O)=O

InChI Key InChIKey=GFMBLHQCFVJLBD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85278   

TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli (strain K12))
University of Ljubljana

LigandPNGBDBM85278(HEA derivative, 7e)
Affinity DataIC50: 5.40E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2012
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Ljubljana

LigandPNGBDBM85278(HEA derivative, 7e)
Affinity DataIC50: 1.20E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2012
Entry Details Article
PubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli (strain K12))
University of Ljubljana

LigandPNGBDBM85278(HEA derivative, 7e)
Affinity DataIC50: 5.60E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2012
Entry Details Article
PubMed