BDBM85254 4,6-dioxo-piperidine-2-carboxylic acid, 3

SMILES [O-]C(=O)[C@@H]1CC(=O)CC(=O)N1

InChI Key InChIKey=JIOAUMVDGKPIAF-UHFFFAOYSA-M

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85254   

TargetDihydroorotase(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  7.60E+7nMpH: 7.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2012
Entry Details Article
PubMed
TargetDihydroorotase(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  2.10E+8nMpH: 8.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2012
Entry Details Article
PubMed
TargetDihydroorotase(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  4.40E+8nMpH: 9.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2012
Entry Details Article
PubMed