BDBM85166 CAS_3292447::NSC_3292447::SB 216641::US20240166639, Example SB41

SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1OCCN(C)C

InChI Key InChIKey=JRNUKVFYILMMLX-UHFFFAOYSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 85166   

Target5-hydroxytryptamine receptor 1B(Human)
Leukos Biotech

US Patent
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  0.600nMAssay Description:Serotonin 5-HT1B receptor competition binding experiments were carried out in a polypropylene 96-well plate. In each well was incubated 5 μg of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 1B(Human)
Leukos Biotech

US Patent
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Leukos Biotech

US Patent
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Leukos Biotech

US Patent
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  7.94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  31.6nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  50.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  50.1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Leukos Biotech

US Patent
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  143nMAssay Description:Serotonin 5-HT2A receptor competition binding experiments were carried out in a polypropilene 96-well plate. In each well was incubated 80 μg of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  158nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  1.58E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi:  3.16E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85166(CAS_3292447 | NSC_3292447 | SB 216641 | US20240166...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed