BDBM85122 Thr1 inhibitor, 1

SMILES C=CC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=FOTCGZPFSUWZBN-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 85122   

TargetCyclin-dependent kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomoserine kinase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataKi:  3.20E+4nM ΔG°:  -6.37kcal/molepH: 7.5 T: 2°CAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed