BDBM84518 Sulindac analogue, 15

SMILES CCC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccoc1

InChI Key InChIKey=SYZJSPFCXVXDAA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 84518   

TargetVascular endothelial growth factor receptor 2(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84518(Sulindac analogue, 15)
Affinity DataIC50: 5.00E+3nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84518(Sulindac analogue, 15)
Affinity DataIC50: 900nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84518(Sulindac analogue, 15)
Affinity DataIC50: 3.00E+3nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84518(Sulindac analogue, 15)
Affinity DataIC50: 1.00E+3nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed