BDBM83846 5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one::MLS002701556::SMR001565157::cid_371509

SMILES CN(C)CCNc1ccc2ncn3c2c1c(=O)c1cc(O)ccc31

InChI Key InChIKey=NXTYWYBBZCKFPD-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 83846   

TargetOrotidine 5'-phosphate decarboxylase(Aspergillus niger)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataEC50: >6.62E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetProbable global transcription activator SNF2L2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataEC50:  1.15E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50: 296nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed