BDBM8375 N-[6-(3-methanesulfonamidophenyl)-1H-indazol-3-yl]cyclopropanecarboxamide::indazole analogue 17

SMILES CS(=O)(=O)Nc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1

InChI Key InChIKey=FUQAHBLEGDXXKS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8375   

TargetGlycogen synthase kinase-3 alpha(Human)
Glaxosmithkline

LigandPNGBDBM8375(N-[6-(3-methanesulfonamidophenyl)-1H-indazol-3-yl]...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8375(N-[6-(3-methanesulfonamidophenyl)-1H-indazol-3-yl]...)
Affinity DataIC50: 1.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM8375(N-[6-(3-methanesulfonamidophenyl)-1H-indazol-3-yl]...)
Affinity DataIC50: 220nMAssay Description:Inhibition of AAK1 (unknown origin) using Fos-Nfluc, Cfluc-kinase and rabbit reticulate lysate system after 1 hr by split luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM8375(N-[6-(3-methanesulfonamidophenyl)-1H-indazol-3-yl]...)
Affinity DataIC50: 220nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed