BDBM8347 6-aryl-pyrazolo[3,4-b]pyridine analogue 11::N-[6-(2-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamide

SMILES COc1ccccc1-c1ccc2c(NC(=O)C3CC3)n[nH]c2n1

InChI Key InChIKey=VJTFFQVPUOHSOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8347   

TargetGlycogen synthase kinase-3 alpha(Human)
Glaxosmithkline

LigandPNGBDBM8347(N-[6-(2-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3...)
Affinity DataIC50: 1.59E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM8347(N-[6-(2-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed